Analytical Method Essay Example | Topics and Well Written Essays - 750 words

Analytical Method - Essay ExampleThis organise the problem statement for the article thereby triggering the researchers to seek for the most appropriate tools and techniques for achieving their objectives. In which case, the researchers provide the a priori background asserting that the chemical analysis of GSR can either focus on inorganic or organic components of the analyte therein. Intuitively, flame ionization detector (FID), thermal energy analysis (TEA), electron intrigue detector (ECD) and mass spectrometry (MS) together with Gas chromatography are important aspects which could be considered in this OGSR analysis.For the methods and materials, the employ of MS/MS mode guided in explicit identification of target analyte. The researchers majorly focused on liquid chromatography tandem mass spectrometry (LCMS/MS) coupled with GC as evident in the use of LCMS grade methanol used in the mobile phase and in chromatographic analysis was performed on an Agilent 1200 Series HPLC s ystem coupled with a hybrid quadrupole snip-of-flight mass spectrometer. The QTOF system was gist to facilitating analysis in MS or MS/MS mode. The researchers carried out accurate mass measuring stick of the precursor ion, within MS spectra, mass measurement of the most specific product ion, and the retention time of the analyte compared with the retention time of the standard. Swabs were compared with home-modified tape lift supports covered with a PTFE layer to determine the better sampling technique. The modified tape lift provided better extraction recoveries and enabled the analysis of inorganic and organic GSR simultaneously.In Optimization of LCQTOF in MS/MS mode parameters, different columns were tested to ensure optimization of the account of the mobile phase through unequivocally separating and ionizing the analytes. In which case, chances for getting false positive and false detrimental results